
Dr Samantha Tay
Medical Director, Aesthetic Physician
MBBS NUS, Former KKH Surgical Resident
Dr Samantha leads Nexus with a surgeon's precision. Skin biology first, needle second.
Written by Dr

How a doctor decides between botulinum toxin and dermal fillers
If you are weighing botulinum toxin against dermal fillers, start with what is causing the line or hollow you see. Both are injections, but they do different jobs. The toxin relaxes the muscle that creases the skin, and a filler restores volume where it has been lost.

Fat freezing or liposuction, and what decides which one suits you
If a pocket of fat has stayed put through diet and exercise, you may be weighing fat freezing against liposuction. Fat freezing cools the fat through the skin, with no cut, while liposuction is an operation that removes fat by suction. In a 2020 study of 231 Asian patients, the treated fat layer measured 19.2% to 22.8% thinner after fat freezing, depending on how it was measured. None of the studies we reviewed compares the two directly, so none shows which works better. The choice starts with an examination of your fat, skin and muscle.

Pico laser or Q-switched laser for pigment, and which suits your skin
If you are choosing between a pico laser and a Q-switched laser for pigment, the two differ in how long each pulse of light lasts. A Q-switched laser fires pulses measured in nanoseconds, and a pico laser fires pulses measured in picoseconds. Nine small trials described here set the two side by side. In 5 of 9 the clearance did not differ significantly, all of them on melasma or tattoos. In the other 4 the picosecond side showed greater clearance, three of them on sun spots and nevus of Ota. Which one suits you depends on your kind of pigment, your skin and how the laser is set.

Radiofrequency or HIFU for skin tightening, and which layer each one works on
If your face or neck has started to loosen, you may be weighing radiofrequency against high-intensity focused ultrasound (HIFU). Radiofrequency passes an electric current through the skin, while HIFU focuses ultrasound at points beneath the surface. A 2024 study describes them working at different depths, and no study we found ranks one above the other. Published improvement rates for focused ultrasound run from 58% to 92%, depending on the study and on who does the rating, so the numbers need reading with care. We found no pooled rate for radiofrequency.

Oral Semaglutide vs Tirzepatide: What the Daily Tablet Can and Cannot Do
You want the weight result without the weekly injection. Before you ask for the tablet, there is one fact about how it is registered in Singapore that changes the conversation.

Profhilo vs Rejuran: How to Choose the Right One for Your Skin
Narrowed your skin booster choice down to Profhilo or Rejuran? They are not rivals. They fix different things. Here is how Dr Samantha decides which one your skin actually needs.
Twenty minutes with Dr Samantha.
Speak with Dr Samantha to find out which protocol fits your skin, your goal, and your timeline.
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