Dull skin despite consistent skincare
Polynucleotide signalling rebuilds dermal quality where retinols and vitamin C can't reach. Most relevant for patients in their 30s-40s starting to see surface dullness despite a stable skincare routine.
Twenty minutes with Dr Samantha first. A Rejuran Healer in Singapore alone delivers a base-level polynucleotide response. The Signature Glow Booster layers Rejuran Healer (polynucleotide healer) with amino acids and peptides for the texture and glow most patients are actually chasing, same 3-session course but a visibly different result. Most patients pick the layered mix once they understand the difference. Individual results vary.
PN I (under-eye, 1ml)
PN Healer 2ml
Teosyal Redensity 1 (1ml)
Signature Glow Booster Eye
Nucleofill Strong 1.5ml
Signature Glow Booster (face)
Nucleofill Strong 3ml
Rejuran Healer (polynucleotide healer) is a salmon-DNA-derived injectable. The polynucleotide fragments signal fibroblast activity in the dermis, stimulating collagen and elastin production over 8 to 12 weeks. It works at the dermal layer through fragments that are biocompatible and gradually absorbed.
Rejuran Healer alone is good for skin-quality response. For patients who want more visible glow + texture change, Dr Samantha layers Rejuran Healer with amino acids and peptides in her Signature Glow Booster mix.
Skin assessment + protocol confirm
Dr Samantha reviews dermal hydration, texture, recent treatments. Confirms Rejuran Healer standalone vs Signature Glow Booster mix.
Numbing cream + skin prep
Topical anaesthetic across the face. Skin cleaned with sterile prep.
Dermal injection
Fine-needle injections across the face surface. Multiple small placements per cheek + forehead + chin. Minimal discomfort.
Cool down + aftercare brief
Cool compress on injection points. Dr Samantha walks through 48-hour aftercare and session 2 booking 4 weeks out.
| Concern | Typical sessions | Interval | Duration of results |
|---|---|---|---|
| Rejuran Healer standalone full course | 3 sessions | 4 weeks apart | Result visible 8-12 wks; lasts 4-6 months |
| Signature Glow Booster full course | 3 sessions | 4 weeks apart | More visible glow + texture; lasts 5-7 months |
| Maintenance after first course | 1 per cycle | Every 4-6 months | Re-engages the polynucleotide response |
| PN I (under-eye) | 3 sessions | 4 weeks apart | 4-6 months under-eye tone improvement |
Maintenance cadence is matched to skin response, not a fixed package.
Rejuran Healer results build over weeks, not days. Most patients notice subtle skin-quality change around week 3, with collagen remodelling continuing through month three. The result is healthier-looking skin texture and modest glow lift; it is not a transformation. Individual results vary.
On before-and-after imagery for Rejuran Healer in Singapore: Dr Samantha keeps doctor-vetted comparison photos in consultation only. We deliberately don't run paid-ads testimonials or before-after creatives in body copy on this page, per HCSA Reg 5(1)(a) (implied-result claims) and Reg 5(1)(f) (testimonials in medical advertising). Patients who want to see real outcome examples discuss them with Dr Samantha at the consultation.
Rejuran Healer 2ml is SGD 600 per 2ml session. The standard 3-session course is SGD 1,800. PN I (under-eye 1ml) is SGD 500 per session.
Polynucleotide booster protocols are not Medisave-claimable. The 20-minute consultation with Dr Samantha is SGD 80, fully credited toward any treatment booked.
Looking at other Rejuran variants? See the Rejuran skin booster overview for HB Plus, S, and the Signature Glow Booster mix.
Settle the injection points
Avoid pressure on the face for 24 hours. No facials, no makeup over injection points for 12 hours. Cool compress for 10 min if any tenderness.
Restore the barrier
Sunscreen SPF 50 daily. Hyaluronic acid + ceramide moisturiser. Skip retinoids + vitamin C serums + exfoliants for 7 days.
Session 2 booking
Book session 2 four weeks after session 1. Full polynucleotide response builds over 8-12 weeks across the course.
Esther sends a brief aftercare summary via WhatsApp post-session.
Twenty minutes with Dr Samantha. Consultation SGD 80, fully credited toward any treatment that follows.
111 Somerset Road, #03-19, TripleOne Somerset, Singapore 238164
Mon to Fri 10am to 8pm · Sat 10am to 5pm · Sun closed