Your Skin Stops Making Collagen After 25.

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Polynucleotide Skin boosters Restarts It

Salmon DNA therapy that works at the dermis level, where creams and serums cannot reach. Stimulates your own collagen production, repairs skin cells, and restores hydration from within.

PolyNucleotide Skinbooster

$380* Nett

No Hidden Charges

*Terms and Conditions Apply

What Is Polynucleotide Skin Booster and How Does It Work?

Polynucleotide (PN) skin boosters use fragments of salmon DNA to activate your skin's natural repair process. Unlike hyaluronic acid fillers that add volume, PN works at the cellular level to stimulate fibroblasts, the cells responsible for producing collagen.

The treatment works through three mechanisms:

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Collagen Stimulation

Activates fibroblasts to produce new collagen, improving skin firmness and elasticity.

🛡️
Cell Repair and DNA Protection

Accelerates repair of damaged skin cells and protects against further DNA damage.

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Deep Hydration

Penetrates the dermis layer where topical creams cannot reach, making skin more supple and radiant.

This is not a surface treatment. It is a medical-grade skin rejuvenation protocol that works from within.

Let Dr Samantha Explain How PolyNucleotide Skinbooster can help change up your skin

What Are the Different Types of Polynucleotides?

In Singapore, there are three different types of polynucleotides available. Each formulation is tailored to address specific skin issues. All formulations feature highly purified polynucleotides sourced from salmon.

HEALER

Polynucleotide Injection

For damaged and aged skin

Specifically formulated to promote total skin healing and rejuvenation. Strengthens the skin barrier, boosts collagen production, and improves elasticity across the entire face.

Learn more about PN Healer →
SCAR

Polynucleotide Injection S

For acne scars and texture

Promotes collagen production and tissue remodelling to treat acne scars and smooth out the skin. Higher concentration formula with greater viscosity for deeper penetration.

Learn more about PN Scar →
EYE

Polynucleotide Injection I

For the delicate eye area

Specifically targets crow's feet, fine lines, wrinkles, and dark circles around the eyes. More fluid formula that is safe for thin under-eye skin without causing lumps.

Learn more about PN Eye →

Polynucleotide Skinbooster vs Profhilo Vs others

Skinbooster Comparison Table

Is This Treatment Right for You?

This treatment is for you if:

  • ✅ Fine lines and wrinkles appearing on face or around eyes
  • ✅ Dull, rough, or uneven skin texture
  • ✅ Enlarged pores
  • ✅ Acne scars or post-acne skin damage
  • ✅ Loss of skin elasticity and firmness
  • ✅ Sun damage and pigmentation concerns
  • ✅ Wanting preventive anti-aging maintenance

This treatment may not be suitable if:

  • ❌ Active skin infection or inflammation in treatment area
  • ❌ Known allergy to salmon or seafood (consult doctor first)
  • ❌ Pregnant or breastfeeding
  • ❌ Currently on blood thinners (consult doctor)

Polynucleotide Skin Booster Pricing in Singapore

Treatment Starting Price Sessions
PN with Microneedling From $380 3-4 sessions
PN Healer (manual injection) From $350 3-4 sessions
PN Eye (under-eye area) From $300 2-3 sessions
PN HydroBoost (PN + HA) From $350 3-4 sessions

All prices include consultation. No hidden packages. No hard sell.

What affects the cost:
  • Which PN variant is used (Healer, Eye, Scar, HydroBoost)
  • Treatment area size (full face vs targeted area)
  • Number of sessions recommended
  • Whether combined with other treatments (laser, fillers)

Combining Polynucleotide with Other Treatments

Polynucleotide skin boosters work well alongside other treatments for enhanced results:

Pico Laser

Laser treats pigmentation, PN repairs and regenerates skin afterwards

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Profhilo

Profhilo provides HA scaffolding, PN adds cellular repair on top

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Dermal Fillers

Fillers restore volume, PN improves surrounding skin quality

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Acne Scar Treatment

PN Scar variant combined with subcision for deep scars

Dr Samantha will design a combination protocol based on your specific skin concerns during consultation.

Polynucleotide Booster Details

Timeframe What to Expect
Immediately Skin feels more hydrated. Mild redness is normal.
1-2 weeks Hydration and texture improvements become visible.
4-6 weeks Full results appear. Collagen remodelling peaks.
3-4 sessions Optimal results. Most patients complete 3-4 sessions spaced 4 weeks apart.
6-12 months Results last. Maintenance sessions recommended every 6-12 months.

Post-Treatment Care Instructions

🔴
Mild Redness is Normal

Subsides within 24 hours. Small bumps may appear and resolve within a day.

🚫
Avoid Touching

Do not touch the treated area for at least 12 hours.

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Gentle Skincare Only

Avoid retinoids, AHAs, BHAs for 48 hours. Use gentle moisturiser and SPF 50+.

☀️
SPF 50+ Essential

Apply sunscreen daily for at least 2 weeks after treatment.

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No Makeup for 12 Hours

Let your skin breathe and absorb the treatment.

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Avoid Strenuous Exercise

No intense exercise or direct sun exposure for 48 hours.

Dr Samantha Tay Medical Director Nexus Aesthetic

" Your Treatment is Performed by Dr Samantha Tay"

Dr Samantha Tay

Medical Director, Nexus Aesthetic

  • MBBS 2013
  • KKH Surgeon 4 Years
  • 10+ Years Experience

Strong passion in skin and aesthetics, keeping her updated with the latest aesthetic treatments and developments. All treatments at Nexus Aesthetic are performed by Dr Samantha personally.

Ready to Restore Your Skin's Natural Glow?

All treatments performed by Dr Samantha Tay personally.

Consult Dr Samantha on WhatsApp

PolyNucleotide Skinbooster FAQs

PolyNucleotide Skinbooster is an advanced skin treatment that uses polynucleotides (PN) derived from salmon DNA to rejuvenate, heal, and repair the skin from within. It promotes collagen production, improves skin elasticity, reduces wrinkles, and enhances overall skin texture and hydration.

PolyNucleotide Skinbooster works by injecting polynucleotides into the skin, which stimulate cell regeneration, increase collagen production, and promote skin healing. This results in smoother, firmer, and more youthful-looking skin over time.

PolyNucleotide Skinbooster is effective for treating a wide range of skin concerns, including:
– Fine lines and wrinkles
– Dull and rough skin texture
– Enlarged pores
– Acne scars
– Skin laxity and loss of elasticity
– Sun damage and pigmentation

Yes, PolyNucleotide Skinbooster is a safe treatment. It uses polynucleotides derived from salmon DNA, which are highly biocompatible with human skin. Clinical studies have shown that PolyNucleotide is well-tolerated, with minimal side effects.

You may notice an improvement in skin hydration and texture immediately after treatment. However, the full effects, such as increased collagen production, firmer skin, and reduction in wrinkles, will develop gradually over 4–6 weeks as your skin regenerates.

For optimal results, it is typically recommended to undergo a series of 3–4 treatments spaced 4 weeks apart. Maintenance treatments can be done every 6–12 months to sustain results.

PolyNucleotide Skinbooster has minimal downtime. You may experience some mild redness, swelling, or small bumps at the injection sites immediately after the treatment, but these usually subside within a few hours to a day.

Yes, PolyNucleotide Skinbooster is suitable for all skin types and is especially beneficial for those looking to improve skin texture, elasticity, and overall appearance. It’s ideal for individuals who want to address early signs of aging or repair damaged skin.

Yes, PolyNucleotide Skinbooster can be combined with other aesthetic treatments such as lasers, microneedling, or fillers to enhance overall results. Consult with your doctor to develop a personalized treatment plan based on your skin’s needs.

PolyNucleotide Skinbooster is generally well-tolerated with minimal risks. The most common side effects include slight redness, swelling, or bruising at the injection sites, which typically resolve within a few days. Rarely, allergic reactions or infections may occur, so it’s important to have the treatment performed by a qualified professional.

The effects of PolyNucleotide Skinbooster can last 6–12 months depending on your skin condition and maintenance treatments. Regular treatments are recommended to maintain the skin’s rejuvenated appearance.